The function of REM, or any other stage of sleep, can currently only be conjectured. A rational evaluation of the role of REM in memory processing requires systematic testing of hypotheses that are optimally derived from a complete synthesis of existing knowledge. Our view is that the large number of studies supporting a relationship between REM-related brain activity and memory is not easily explained away. [Vertes & Eastman].

As one of America’s "public intellectuals," John Dewey was engaged in a lifelong struggle to understand the human mind and the nature of human inquiry. According to Thomas C. Dalton, the successful pursuit of this mission demanded that Dewey become more than just a philosopher; it compelled him to become thoroughly familiar with the theories and methods of physics, psychology, and neurosciences, as well as become engaged in educational and social reform. Tapping archival sources and Dewey’s extensive correspondence, Dalton reveals (...) that Dewey had close personal and intellectual ties to scientists and scholars who helped form the mature expression of his thought. Dewey’s relationships with F. M. Alexander, Henri Matisse, Niels Bohr, Myrtle McGraw, and Lawrence K. Frank, among others, show how Dewey dispersed pragmatism throughout American thought and culture. (shrink)

This essay traces Newman’s rich legacy in modern American literature in the writings of three prominent American writers of the last century: F. Scott Fitzgerald, who plays off of Newman’s definition of a gentleman in his The Beautiful and Damned ; Sinclair Lewis, who connects the figure of Carlyle Vesper to Newman in Gideon Planish ; and Flannery O’Connor, who mentioned Newman in four published letters, and whose artistic vision was shaped appreciably by Newman’s Apologia and his Grammar of (...) Assent. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 331 The Great Dissent: John Henry Newman and the Liberal Heresy. By ROBERT PATTISON. New York: Oxford University Press, 1991. Pp. xiii +231. $29.95. This extremely provocative and elegantly written study of John Henry Newman's struggle with "liberalism" argues that Newman was a genuine rebel whose solitary voice needs to be heard, as much today as then, but whose project was, in the end, eminently unsuccessful. The (...) preface announces that the purpose of the book is to " establish Newman 's impeccable credentials as a failure," and the suggestion that " the totality of his failure is the measure of his grandeur as a critic of our culture" leads to the appraisal that Newman's true "intellectual counterparts " were Marx and Nietzsche and Lenin, rather than Arnold or Carlyle (vi-viii, 53). As "the single unwavering but articulate voice raised against liberalism in all its incarnations," Newman indirectly offers an " invaluable " description of the thought against which he battled, but his importance, the author suggests, lies in his utter failure to make a dent in the century of thought following him: " the victory of everything Newman despised makes his defeated and unfashionable view of Western civilization interesting not merely as a consistent critique of what has come to pass, hut as one of the few intelligible alternatives to the ideological monopoly of liberalism " (53). That alternative, a " consistent view of the world opposed to liberalism root and branch, sharing none of its premises and despising all of its works is an inestimable benefit, for no one more than the liberal himself," for without an "honest and unforgiving voice" like Newman's, the liberal " would smugly assume that the paradoxical tenets of his creed are... self-evident truths" (215). On the one hand, Newman's value lies in challenging liberalism's complacency, and treating "the ugliest manifestations of liberalism with the contempt they deserve but rarely provoke" (215). Moreover, Pattison allows that Newman offers an " acute refutation of its [liberalism's] major premises " (53) (if " refutation " is the ' achievement ' word I think it is, this seems inconsistent on Pattison's part). On the other hand, Newman's value lies precisely in failing to undermine liberalism-while he reminds liberalism that it is a heresy, thus provoking its vitality, it is only insofar as liberalism remains vital that " the possibilities of relative decency and tolerant forbearance remain alive" (216). The author argues, in other words, that Newman's attack on liberalism hits the mark with respect to liberalism's "ugliest manifestations," hut it is, unfortunately, tied to a theory of belief which entails an intolerant dogmatism. Newman is, in the end, a peculiar figure, described as 332 BOOK REVIEWS important and valuable (and even possibly correct-189), yet, none· theless, insignificant, "trivial" (8), and even "absurd" (143); like the Oxford Movement with which he is associated, he said to have made an "impression" without making an "impact" (25), and that, according to Pattison, is a blessing for those care about the liberal cause oftoleration (65, 178). Pattison begins in earnest his exploration of Newman's response to his age by examining his particular response to one critical, yet typical, opponent: "The combat with Renn Dickson Hampden epitomizes the process by which Newman determined the narrow compass of truth and formed his reply to the heresies of liberalism " (60). The " almost pathological detestation " of Hampden which the author attributes to Newman (77, n.40) is the response to principles put forth by Hampden which Newman saw as "the social expression of Socinianism," which was itself only a reincarnation of the Ari.an heresy (76). Hampden's heresy, on this view, grew out of Arianism-to understand that "is to see how Newman formed the standards of truth by which he condemned the modern world" (76). For Newman, "the modern world is a realization of Socinian beliefs," " the complex of contemporary civilization originated in the distorted beliefs of Arius" (198-99), and Arianism (Hampden's heresy, liberalism) raised the pressing question "what kind of truth could words express" (107). Pattison presents Newman's understanding of liberalism from two somewhat different perspectives-HberaHsm is not only anti-dogmatic, it also claims that one... (shrink)

ETUDES DE PHILOLOGIE 38 ETD'HISTOIRE JEANETTE MA BEER Narrative Conventions of Truth in the Middle Ages GENEVE ...

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Johanna Knapstein,1 Daniel Grimm,1 Marcus A Wörns,1 Peter R Galle,1 Hauke Lang,2 Tim Zimmermann111st Department of Internal Medicine, Johannes Gutenberg-University, Mainz, Germany; 2Department of General, Visceral and Transplantation Surgery, Johannes Gutenberg-University, Mainz, GermanyIntroduction: Hepatitis C virus reinfection occurs universally after liver transplantation, with accelerated cirrhosis rates of up to 30% within 5 years after liver transplantation. Dual antiviral therapy with pegylated interferon-2a and ribavirin only reaches sustained virological response rates of ~30% after liver transplantation. With the approval of viral NS3/4A (...) protease inhibitors telaprevir, boceprevir, and simeprevir and the NS5B polymerase inhibitor sofosbuvir, combination therapy offers new therapeutic options for HCV-infected patients, resulting in considerably higher sustained virological response rates in the nontransplant setting. Case presentation: We report three cases of TVR-based triple antiviral therapy in HCV genotype 1 reinfected patients after liver transplantation, of whom a 57-year-old Caucasian female and a 43-year-old Caucasian male were therapy naïve, and a 49-year-old Caucasian male patient was pretreated ineffectively. After 4 weeks of therapy, viral load decreased one to three log10 and became negative in weeks 6 to 8 in the therapy naïve patients. The pretreated patient showed a negative viral load in week 4. TVR was administered over 12 weeks, 750 mg thrice daily. Doses of immunosuppression with cyclosporine were reduced four to six fold. Initial peg-IFN and RBV doses ranged from 135–180 µg/week and 800–1,200 mg/day, according to the patient's body weight. Doses of peg-IFN and RBV were adapted to 90–135 µg/week and 400–800 mg/day after 2 to 12 weeks of protease inhibitor therapy. Dual therapy was continued for 36 weeks with total treatment duration of 48 weeks in the therapy naïve patients leading to a sustained virological response 12 weeks after the end of therapy. In the pretreated patient a breakthrough was detected in week 24 and therapy was discontinued. Overall, antiviral therapy was well tolerated. Side effects included dysgeusia and anemia leading to erythropoietin application and blood transfusions. Conclusion: This case series emphasizes that triple therapy with TVR is an efficient treatment for therapy naïve HCV genotype 1 reinfected patients after liver transplantation. But therapeutic options for pretreated patients require improvement. Keyword: cyclosporine, interferon, ribavirin, hepatitis C, protease inhibitor. (shrink)

This article is devoted to the characterization of the basin of attraction of pattern solutions for some slow–fast reaction–diffusion systems with a symmetric property and an underlying oscillatory reaction part. We characterize some subsets of initial conditions that prevent the dynamical system to evolve asymptotically toward solutions which are homogeneous in space. We also perform numerical simulations that illustrate theoretical results and give rise to symmetric and non-symmetric pattern solutions. We obtain these last solutions by choosing particular random initial conditions.

Two rotational bands have been identified and characterized in the proton-magic N = Z + 1 nucleus Ni-57. These bands complete the systematics of well-and superdeformed rotational bands in the light nickel isotopes starting from doubly magic Ni-56 to Ni-60. High-spin states in Ni-57 have been produced in the fusion-evaporation reaction Si-28(S-32, 2p1n)Ni-57 and studied with the gamma-ray detection array GAMMASPHERE operated in conjunction with detectors for evaporated light charged particles and neutrons. The features of the rotational bands in Ni-57 (...) are compared to those of neighbouring isotopes and interpreted by means of configuration-dependent cranked Nilsson-Strutinsky calculations. The two observed high-spin bands are considered signature partners and assigned to configurations with one 1g(9/2) proton and one 1g(9/2) neutron, resulting in an unambiguous understanding of the energetically favoured signature alpha = -1/2 band but a somewhat less satisfactory description of the signature alpha = +1/2 band. (shrink)

بالحرف نفهم الوجود، ونكتشفُ مُعَمَّيَاتِه وملابساته.فالوجود حرف، والحرف وجود، فهما معا يتماهيان، وهما معا يتبادلان الأدوار في مرآة الحياة والذاكرة والدين والأسطورة و المخيال، وفي فضاء الترميز بالقوة القَوَوِيَّةِ والتجريد المتعالي. وإذا كانت حبة الرمل تختزن الصحراء وتؤشر عليها، وقطرةُ الماء تختزل البحرَ وتومئ إليه، ونبضةُ العِطر تحوز الأزهارَ وتدل عليها، فإن الحرف هو كذلك يمثِّل كثافة الوجود في أعالي أعاليها، فهو الشجرة الرامزة إليه أونطولوجيا. إذْ من هذه الشجرة خرج الأمر الإلهي، فصار كونا ووجودا هو عبارة عن شجرة الكون (...) التي يُجَسِّد كل جزء من أجزائها حرَكِيَّةَ الوجود، وتوهجَ اختلافاته، وتناغمَ إيقاعاته، وتشابكَ دلالاته. إن الوجود حرف لا تكون الكتابة إلا به، والخلْق كتابة، والكتابة غرْسٌ، والغرس نفْسٌ، والنفْس وجود.وهكذا تبتدئ دائرة الوجود بالحرف وتنتهي به وإليه، فخلْقُ آدم وتركيبُه له دلالة على هذا المَنْحَى، فهو وسلالته يشبهان رمزيا في حياتهما حروفَ الأبجدية في بدايتها ونهايتها، فهما يدخلان إلى هذه الحياة على شكل ألِفٍ، ويخرجان منها على شكل ياءٍ.فالعِلم بالأسماء موضوع في قلب آدم، وتصْويرُها في صدره، وتعبيرها فيما بين حلْقه إلى شفتيه، فالقلبُ طَرَفٌ للعلْم، والصدر طَرَفٌ للتصاوير، والفم طَرَفٌ للتعبير. فالعالمُ في أول ظهورٍ له كان على صورة الإنسان، وصورة الإنسان هي صورة الحق. فصورتُه التي على صورة الحق تُؤَهِّلُه لمعرفة الحق من خلال معرفته لذاته الإنسانية. (shrink)

_Essays on Politics and Society_ brings together the most significant writings on the topic by the acclaimed Victorian historian, social critic, and essayist Thomas Carlyle. This volume includes some of his most well-known and influential pieces, such as "Characteristics" and "Chartism." In keeping with the Norman and Charlotte Strouse Edition of the Writings of Thomas Carlyle, these essays are accompanied by a thorough historical introduction to the material, extensive notes providing historical and cultural context while expanding on references (...) and allusions, and a textual apparatus that carefully details and explains the editorial decisions made in reconciling the editions of each essay. (shrink)

This article sets out to counteract HM Evans’s “fair’s fair argument” in support of abolishing veto to research participation. Evans’s argument attempts to assimilate ordinary clinical practice to clinical research. I shall refer to this attempt as “assimilation claim”. I shall attempt to show that this assimilation, as it is carried out in Evans’s argument, is misleading and, ultimately, logically undermines the conclusion. I shall then proceed to show that when the fair’s fair argument is proposed independently of the assimilation (...) claim, Evans’s conclusion is not unavoidable and possible alternatives are equally open within the terms of the argument itself. (shrink)

To understand the goals of communist education and shaping of the human being we need deep study of human activity.

Authority in Morals: An Essay in Christian Ethics. By Gerard J. Hughes On Human Nature. By Edward O. Wilson Democracy and Ethical Life. By Claes G. Ryn The Foundations of Modern Political Thought. By Quentin Skinner. 2 vols. Phenomenology and the Social World: the Philosophy of Merleau‐Ponty and its Relation to the Social Conscience. By Laurie Spurting Philosophical Foundations of the Three Sociologies. By Ted Benton Christianity and the World Order. By Edward Norman. Oxford, Oxford University Press, 1979, £3.50. The (...) Stoics. Edited by John M. Rist Descartes. By Margaret D. Wilson Physicalism. By K.V. Wilkes Kierkegaard as Educator. By R.J. Manheimer Two Ages: The Age of Revolution and the Present Age. By Søren Kierkegaard, translated and edited by Howard and Edna Hong Parables of Kierkegaard. Edited by Thomas C. Oden Thomas Carlyle: ‘Cahinist without the Theology’. By Eloise M. Behnken The Praise of 'Sons of Bitches’. By James V. Schall The Inner Eye of Love. By William Johnston The River Within. By Christopher Bryant The Religious Imagination and the Sense of God. By John Bowker Old Testament Theology: A Fresh Approach. By Ronald E. Clements What is a Gospel? By Charles H. Talbert Urchristliche Prophetic. By Gerhard Dautzenberg Amphttochii Icontensis Opera. Edited by Cornells Datema Man and Nature in the Renaissance. By Allen G. Debus The Church in Late Victorian Scotland 1874–1900. By Andrew L. Drummond and James Bullock. Ppix, 342, Edinburgh, The St Andrew Press, 1978, £10.50. From Office to Profession: The New England Ministry 1750–1860. By Donald M. Scott Bemard‐Lazare: Anti‐Semitism and the Problem of Jewish Identity in Late Nineteenth Century France. By Nelly Wilson. (shrink)

Quantum mechanical measurements on a physical system are represented by observables - Hermitian operators on the state space of the observed system. It is an important question whether all observables may be realized, in principle, as measurements on a physical system. Dirac’s influential text ( [1], page 37) makes the following assertion on the question: The question now presents itself – Can every observable be measured? The answer theoretically is yes. In practice it may be very awkward, or perhaps even (...) beyond the ingenuity of the experimenter, to devise an apparatus which could measure some particular observable, but the theory always allows one to imagine that the measurement can be made. This Letter re-examines the question of whether it is possible, even in principle, to measure every quantum mechanical observable. Unexpectedly, ideas from com-. (shrink)

There is a difference between the private and social cost of preserving the past. While it may be privately rational to forget the past, the social cost is significant: we fail to see that Classical political economy is a polemic against racism. The past is a rich source of surprises and debates, and resources on the Web are uniquely suited to teaching such wide-ranging debates. Our ASecret History of the Dismal Science on the web, provides a rich series of windows (...) on the literary and analytical texts, and the artwork, that figured in the debates. Students who read Smith juxtaposed with Whitman, who read the Carlyle-Mill exchange, and who see these images, understand the debate the way a student who reads only the Wealth of Nations, Ricardo's Principles, or John Stuart Mill cannot. (shrink)